Which combination is listed as an adjunctive option for bipolar or related conditions?

Which combination is listed as an adjunctive option for bipolar or related conditions?

• A. Fluoxetine/olanzapine combo
• B. Quetiapine
• C. Lurasidone
• D. Ziprasidone

Answer: (A)

In bipolar depression, adding an antidepressant to an antipsychotic as a fixed-dose combination is a recognized adjunctive strategy to boost response while supporting mood stabilization. The fluoxetine/olanzapine pair fits this role exactly: it combines an antidepressant with an antipsychotic in one option to be added to a mood stabilizer when symptoms need more than mood stabilization alone. The other choices are single-agent antipsychotics and, while they’re used in bipolar disorder, they aren’t presented as a combined antidepressant- antipsychotic option.

In bipolar depression, adding an antidepressant to an antipsychotic as a fixed-dose combination is a recognized adjunctive strategy to boost response while supporting mood stabilization. The fluoxetine/olanzapine pair fits this role exactly: it combines an antidepressant with an antipsychotic in one option to be added to a mood stabilizer when symptoms need more than mood stabilization alone. The other choices are single-agent antipsychotics and, while they’re used in bipolar disorder, they aren’t presented as a combined antidepressant- antipsychotic option.