Modecate and Prolixin are brand names for which decanoate?

Modecate and Prolixin are brand names for which decanoate?

• A. Fluphenazine decanoate
• B. Fluanxol
• C. Haloperidol decanoate
• D. Zuclopenthixol decanoate

Answer: (A)

Depot antipsychotics use decanoate esters to create long-acting injections. Modecate and Prolixin are the brand names for the decanoate form of fluphenazine, a typical antipsychotic. The decanoate ester slows release after an intramuscular injection, keeping therapeutic drug levels for weeks and helping with adherence in schizophrenia treatment. Other decanoates exist for different drugs (for example, haloperidol decanoate and zuclopenthixol decanoate) and have different brand names, so they’re not associated with Modecate or Prolixin. Therefore, the decanoate in question is fluphenazine decanoate.

Depot antipsychotics use decanoate esters to create long-acting injections. Modecate and Prolixin are the brand names for the decanoate form of fluphenazine, a typical antipsychotic. The decanoate ester slows release after an intramuscular injection, keeping therapeutic drug levels for weeks and helping with adherence in schizophrenia treatment. Other decanoates exist for different drugs (for example, haloperidol decanoate and zuclopenthixol decanoate) and have different brand names, so they’re not associated with Modecate or Prolixin. Therefore, the decanoate in question is fluphenazine decanoate.